Last Updated on: 4th September 2024, 05:12 pm
Summary
| Diagnosis | Sex | Age | Nationality |
|---|---|---|---|
| Optic Nerve Hypoplasia (ONH) / Septooptic Dysplasia (SOD) | Female | 6 years | USA |
| Injections | Cell type | Admission date | Discharge date |
| 7 | UCMSC | December 20th 2018 | January 4th 2019 |
Condition On Admission
Baylie had learning disability. She had Diabetes Insipidus and autistic behaviors. She did not talk but could understand. She was affected by constipation and lack of sleep. She did not walk and she was totally blind from birth but she gained a little bit of sight overtime.
Treatment Schedule
Patient received 6 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) injection and lumbar puncture (LP), as per the schedule below:
| Number | Date | Cell Type | Delivery Method | Side Effects |
|---|---|---|---|---|
| 1 | 2018-12-21 | UCMSC | Intravenous Injection | none reported |
| 2 | 2018-12-25 | UCMSC | Intrathecal Injection | none reported |
| 3 | 2018-12-25 | UCMSC | Retrobulbar Injection | none reported |
| 4 | 2018-12-28 | UCMSC | Intravenous Injection | none reported |
| 5 | 2018-12-28 | UCMSC | Retrobulbar Injection | none reported |
| 6 | 2020-01-02 | UCMSC | Intrathecal Injection | none reported |
| 7 | UCMSC | Intravenous Injection | None |
Condition 6 months after treatment
Condition 6 months after treatment: At the 6 month follow up point, Baylie’s family mentioned: “Baylie can now see up to about 2 to 3 feet. She is starting to focus on things and look at them instead of feeling for them. Amazing improvement. Baylie has muscle tone improvement. She is definitely more active and her posture is way better.” Please see an excerpt from the family’s 6 month assessment below:
| Symptom | Parents’ Assessment of Improvement |
| Ability to focus eyes quickly | Moderate improvement |
| Ability to keep eyes focused for a long time | Small improvement |
| Ability to see hand movement | Significant improvement |
| Ability to see things at a close distance | Significant improvement |
| Ability to see things at a far distance | Moderate improvements |
| Ability to see things clearly | Moderate improvements |
| Able to count fingers | Significant improvement |
| Blindness | Significant improvement |
| Colour vision | Significant improvement |
| Light perception | Significant improvement |
| Night vision | Moderate improvements |
| Nystagmus | Moderate improvements |
| Strabismus | Small improvement |
| Vision in left eye | Significant improvement |
| Vision in right eye | Significant improvement |
| Visual field | Significant improvement |