Manuela and Giulia come from the same region of Brazil. News of Manuela's fundraising efforts introduced Giulia's family to umbilical cord blood stem cells.
While Manuela has optic nerve hypoplasia, Giulia suffers from septo optic dysplasia. Both conditions include underdevelopment of the optic nerve.
Both received transplants of umbilical cord blood stem cells administered at Qingdao's Chengyang's People's Hospital.