Summary
Diagnosis
Sex
Age
Nationality
Cerebral Palsy
Female
13 years
Argentinia
Injections
Cell type
Admission date
Discharge date
8
2012-01-18
2012-02-18
Condition On Admission
The patient had a development delay of movement on the right side of her body since birth. During physical assessment upon her admission to the hospital she was found to be fully alert to her surroundings and her memory and perceptual functions were also normal. The muscle strength, tone, and reflexes of her left sided limbs were normal. Muscle strength of her right limbs was 4/5 and her muscle tone on that side was affected by spasticity. Tendon reflexes on the right side were present.
Treatment Schedule
The patient received 7 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) and intrathecal injections as per schedule below:
Number
Date
Cell Type
Delivery Method
Side Effects
1
2012-01-22
Intrathecal Injection &
Intravenous Injection
headache
2
2012-02-01
none reported
3
2012-02-01
none reported
4
2012-02-03
none reported
5
2012-02-06
none reported
6
2012-02-11
none reported
7
2012-02-15
none reported
Condition at discharge
The side effects noticed after the 2nd injection had resolved without any lasting effects by the end of the treatment. The doctors noted the patient’s right arm movement had gained flexibility and her ability to control her trunk muscles had improved. The patient’s parents commented that their daughter had made some good improvements at the hospital and they were hopeful for further developments in the near future.
Condition 6 months after treatment
The patient’s family sent a small update about their daughter stating that she was able to speak with more fluidity and her right side was not as spastic as before the treatment.
Condition 14 months after treatment
The patient’s family, in the 14 months since treatment, had observed big improvements in their daughter’s quality of life and physical condition. Along with the physical improvements reported in the follow-up survey below, the family also mentioned that her intellectual and language abilities had also greatly improved. Please see an excerpt from the patient’s 14 month assessment below (submitted by the patient’s parents):
Symptom
Assessment of Improvement
Trunk control
Significant improvement
Balance
Significant improvement
Movement in general
Significant improvement
Walking
Significant improvement
Standing up
Moderate improvements
Spasticity
Significant improvement
Overall strength
Significant improvement
Limb muscle strength
Significant improvement
Trunk muscle strength
Significant improvement
Range of movement
Significant improvement
Hand control
Significant improvement
Speech
Significant improvement
General mental ability
Significant improvement
