Patient Story

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Case Study Cerebral Palsy Female, 2 years old, March 2012

Summary

Diagnosis

Sex

Age

Nationality

Cerebral Palsy

Female

2 years

Argentinia

Injections

Cell type

Admission date

Discharge date

7

UCBSC

2012-03-03

2012-04-01

Condition On Admission

The patient was born with encephalopathy and had speech and movement development delays. The patient could not speak, sit, or walk upon admission to the hospital. She could move her limbs, but without any control. Muscle tone in both arms and legs was high.

Treatment Schedule

The patient received 7 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) and intrathecal injections as per schedule below:

Number

Date

Cell Type

Delivery Method

Side Effects

1

2012-03-05

UCBSC

Intravenous Injection

none reported

2

2012-03-07

UCBSC

Intrathecal Injection

none reported

3

2012-03-12

UCBSC

Intrathecal Injection

none reported

4

2012-03-16

UCBSC

Intrathecal Injection

none reported

5

2012-03-21

UCBSC

Intrathecal Injection

none reported

6

2012-03-23

UCBSC

Intravenous Injection

none reported

7

2012-03-28

UCBSC

Intrathecal Injection

none reported

Condition at discharge

The patient had no fever, headaches, or other side effects after transplantation of the stem cells. The doctors reported that the spasticity in her limbs had decreased, the movement of her right arm had become more controlled and flexible, and she had better overall body balance.

Condition 3 months after treatment

The patient’s parents completed the follow-up survey three months after the treatment; they commented that their daughter was now much more active and she had shown a big development in her speech. As for physical improvements, they observed that her trunk muscles had gained much more strength and she was now able to remain seated for longer periods. Her balance had also improved to the point where she was now able to stand with some support for longer periods of time. They felt their daughter’s quality of life had improved since the treatment. Please see the excerpt below from her 3 month follow-up survey (filled out by the patient’s parents):

Symptom

Parents’ Assessment of Improvement

Trunk control

Significant improvement

Balance

Moderate improvement

Movement in general

Moderate improvement

Walking

Moderate improvement

Overall strength

Significant improvement

Limb muscle strength

Moderate improvements

Trunk muscle strength

Significant improvement

Range of movement

Moderate improvements

Fine motor control

Moderate improvements

Hand control

Moderate improvements

Speech

Significant improvement

General mental ability

Significant improvement

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