Patient Story

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Case Study Cerebral Palsy Male, 6 years old, May 2012

Summary

Diagnosis

Sex

Age

Nationality

Cerebral Palsy

Male

6 years

Argentinia

Injections

Cell type

Admission date

Discharge date

6

UCBSC

2012-05-02

2012-06-01

Condition On Admission

The patient’s main presenting complaint was of a movement disorder and development delay since birth. The patient was conscious and his awareness and perceptive functions were normal. He was unable to speak. He could make some movements but was unable to fully control these. His four limbs were spastic.

Treatment Schedule

The patient received 6 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) and intrathecal injections, as per the schedule below:

Number

Date

Cell Type

Delivery Method

Side Effects

1

2012-05-04

UCBSC

Intravenous Injection

none reported

2

2012-05-09

UCBSC

Intrathecal Injection

none reported

3

2012-05-14

UCBSC

Intrathecal Injection

none reported

4

2012-05-18

UCBSC

Intrathecal Injection

none reported

5

2012-05-23

UCBSC

Intrathecal Injection

none reported

6

2012-05-28

UCBSC

Intrathecal Injection

none reported

Condition at discharge

Following stem cell treatment, the patient had no fever, headache or other side effects. The doctors observed an improvement in his sitting balance and trunk control and they also noted his head control was better. The family reported small improvements in their son’s overall physical condition at the time of discharge. Below is an excerpt from the discharge improvement evaluation form filled by the patient’s parents:

Symptom

Assessment of Improvement

Spasticity

Small improvement

Trunk muscle strength

Small improvement

Limb muscle strength

Moderate improvement

Head Control

Small improvement

Range of movement

Small improvement

Involuntary movements

Small improvement

Standing up

Small improvement

Walking

No improvement

Speech (babbling in infants)

Small improvement

Swallowing

Moderate improvement

Appetite

Significant improvement

Learning disability

Moderate improvement

Mood

Moderate improvement

Condition 3 months after treatment

The family reported that their son had gained significant improvements in his quality of life. On the 3-month follow-up form they wrote: “He has improved head control, trunk control and mom and dad can now be said. He is now blowing and making objects with his hands with better control than before, he more firmly takes steps and has improved fine motor skills, now try to place small items in small containers.” Please see as excerpt of his 3-month follow-up report (submitted by the patient’s parents):

Symptom

Assessment of Improvement

Spasticity

Significant improvement

Trunk muscle strength

Moderate improvement

Limb muscle strength

Significant improvement

Head Control

Significant improvement

Range of movement

Moderate improvement

Involuntary movements

Moderate improvement

Balance

Moderate improvement

Standing up

Moderate improvement

Walking

Moderate improvement

Speech (babbling in infants)

Moderate improvement

Swallowing

Moderate improvement

Appetite

Significant improvement

Learning disability

Significant improvement

Mood

Significant improvement

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