Summary
| Diagnosis | Sex | Age | Nationality |
|---|---|---|---|
| Cerebral Palsy | Male | 6 years | Argentinia |
| Injections | Cell type | Admission date | Discharge date |
|---|---|---|---|
| 6 | UCBSC | May 2nd 2012 | June 1st 2012 |
Condition On Admission
The patient’s main presenting complaint was of a movement disorder and development delay since birth. The patient was conscious and his awareness and perceptive functions were normal. He was unable to speak. He could make some movements but was unable to fully control these. His four limbs were spastic.
Treatment Schedule
The patient received 6 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) and intrathecal injections, as per the schedule below:
| Number | Date | Cell Type | Delivery Method | Side Effects |
|---|---|---|---|---|
| 1 | 2012-05-04 | UCBSC | Intravenous Injection | none reported |
| 2 | 2012-05-09 | UCBSC | Intrathecal Injection | none reported |
| 3 | 2012-05-14 | UCBSC | Intrathecal Injection | none reported |
| 4 | 2012-05-18 | UCBSC | Intrathecal Injection | none reported |
| 5 | 2012-05-23 | UCBSC | Intrathecal Injection | none reported |
| 6 | 2012-05-28 | UCBSC | Intrathecal Injection | none reported |
Condition at discharge
Following stem cell treatment, the patient had no fever, headache or other side effects. The doctors observed an improvement in his sitting balance and trunk control and they also noted his head control was better. The family reported small improvements in their son’s overall physical condition at the time of discharge. Below is an excerpt from the discharge improvement evaluation form filled by the patient’s parents:
Symptom
Assessment of Improvement
Spasticity
Small improvement
Trunk muscle strength
Small improvement
Limb muscle strength
Moderate improvement
Head Control
Small improvement
Range of movement
Small improvement
Involuntary movements
Small improvement
Standing up
Small improvement
Walking
No improvement
Speech (babbling in infants)
Small improvement
Swallowing
Moderate improvement
Appetite
Significant improvement
Learning disability
Moderate improvement
Mood
Moderate improvement
Condition 3 months after treatment
The family reported that their son had gained significant improvements in his quality of life. On the 3-month follow-up form they wrote: “He has improved head control, trunk control and mom and dad can now be said. He is now blowing and making objects with his hands with better control than before, he more firmly takes steps and has improved fine motor skills, now try to place small items in small containers.” Please see as excerpt of his 3-month follow-up report (submitted by the patient’s parents):
Symptom
Assessment of Improvement
Spasticity
Significant improvement
Trunk muscle strength
Moderate improvement
Limb muscle strength
Significant improvement
Head Control
Significant improvement
Range of movement
Moderate improvement
Involuntary movements
Moderate improvement
Balance
Moderate improvement
Standing up
Moderate improvement
Walking
Moderate improvement
Speech (babbling in infants)
Moderate improvement
Swallowing
Moderate improvement
Appetite
Significant improvement
Learning disability
Significant improvement
Mood
Significant improvement
