Summary
Diagnosis
Sex
Age
Nationality
Spinal Cord Injury
Male
48 years
Australian
Injections
Cell type
Admission date
Discharge date
6
2018-07-23
2018-08-16
Medical history
The patient was diagnosed with spinal cord injury in 2016 from lifting heavy objects (over 15-20 kg). He had severe lower back pain that caused pain in both legs as well. In may 2016, an MRI scan test result revealed severe central canal and neuroforaminal stenosis at the L4-L5 level due to broad-based disc bulge. As a result, the patient had a laminectomy surgery in L3-L5 and a microdiscectomy surgery in L4-L5 as well as a postoperative rehabilitation program for pain relief.
Condition On Admission
The patient had numbness in both legs with the left leg being more affected. There was muscle weakness in the left leg as well. Dynamic standing balance was rated as fair, muscle endurance was low and there was partial bowel and bladder function impairment. The patient was able to engage in all daily activities, independently.
Treatment Schedule
The patient received 3 umbilical cord blood-derived stem cell (UCBSC) packets and 3 umbilical cord mesenchymal stem cell (UCMSC) packets by intravenous (IV) and intrathecal injections, as per the schedule below:
Number
Date
Cell Type
Delivery Method
Side Effects
1
2018-07-27
none reported
2
2018-07-31
none reported
3
2018-08-03
none reported
4
2018-08-06
none reported
5
2018-08-10
none reported
6
2018-08-14
none reported
Condition at discharge
At the end of the 3 weeks therapeutic program, the patient has shown some improvement in sensation, muscle endurance and dynamic standing balance as follows: The patient has informed us that he has more feeling in his left leg and his right leg feels now normal. Endurance has slightly improved as he is now capable of walking on the treadmill for 15 minutes with a speed up to 5.5 (compared to less than 10 minutes at a slower speed earlier). Dynamic standing balance went from fair/good, to good/normal. By the end of the program the patient could perform one leg standing for 1 minute without support in aquatic therapy.
Condition 12 months after treatment
At the 12 month follow up point the patient reported that he still had numbness in a small area behind the left leg with a little pain but he was feeling better than before the treatment. He rated his improvement in quality of life as moderate. Please see an excerpt from the patient’s 12 month own assessment below:
Symptom
Assessment of Improvement
Bladder control
Moderate improvement
Bowel control
Moderate improvement
Control of body temperature
Significant improvement
Fatigue
Significant improvement
Fine motor control
Moderate improvement
Lower limb muscle tone
Significant improvement
Lower limb sensation
Moderate improvement
Lower limb strength
Moderate improvement
Pain
Moderate improvement
Sexual Function
Moderate improvement
Skin Condition
Significant improvement
Sweating
Significant improvement
Trunk muscle strength
Moderate improvement
Trunk muscle tone
Significant improvement
Trunk sensation
Moderate improvement
Upper limb muscle tone
Significant improvement
Upper limb sensation
Significant improvement
Upper limb strength
Moderate improvement
