Cerebral Palsy, Male, 3 years, February – March 2022

Last Updated on: 4th September 2024, 05:12 pm

Summary

Diagnosis Sex Age Nationality
Cerebral Palsy Male 3 years Latvia
Injections Cell type Admission date Discharge date
8 UCMSC February 23rd 2022 March 17th 2022

Medical history

The patient was diagnosed with cerebral palsy (tetraperesis) following herpes meningoencephalitis. MRI scans revealed severe brain damage on the right side and minor damage on the left. Currently six months old, he exhibits relatively normal development, albeit with weaker left arm movement and slower mobility compared to peers. Physiotherapies and massages, along with home exercises, constitute his treatment regimen. Medications include phenobarbital, acyclovir for herpes, and depakine syrup to prevent seizures, as per EEG recommendations. His mother’s herpes infection during pregnancy and subsequent outbreak during childbirth were noted as relevant medical history.

Condition On Admission

The patient demonstrates limited speech and slower motor skills, though he can roll over, hold his head up, and grasp objects with his right arm. There have been no reported allergies, abnormal bowel movements, or other significant gastrointestinal issues. Despite the herpes infection history, no communicable illnesses are present. Notably, there’s no epilepsy/seizures recorded thus far. With no major surgeries, bedsores, ulcers, or respiratory complications, the patient’s current condition primarily centers around managing cerebral palsy and monitoring his developmental progress.

Treatment Schedule

Patient received 8 packs of umbilical cord derived stem cell (UCMSC) by intravenous (IV) injection and intrathecal injection via lumbar puncture (LP), as per the schedule below:

Number Date Cell Type Delivery Method Side Effects
1 2023-03-07 UCMSC Intrathecal Injection &
Intravenous Injection
none reported
2 2023-03-10 UCMSC Intrathecal Injection &
Intravenous Injection
none reported
3 2023-03-14 UCMSC Intrathecal Injection &
Intravenous Injection
none reported
4 2023-03-17 UCMSC Intrathecal Injection none reported
5 2023-03-12 UCMSC Intrathecal Injection none reported

Condition 12 months after treatment

The patient’s progress post-treatment shows notable improvements in several areas, particularly in speech development and motor skills. Despite initial concerns, the patient has demonstrated progress in verbal communication, attempting two to three-word sentences and actively engaging in speech repetition. Additionally, advancements in physical activities such as puzzle-solving, Lego play, and learning to use bicycle pedals reflect improvements in motor coordination. The patient’s participation in kindergarten with specialized attention and therapy sessions further supports his developmental progress.

Symptom Parents’ Assessment of Improvement
Balance Small improvement
Learning disability Small improvement
Mood disorder Small improvement
Standing up Small improvement
Language functions Mostly able to do
Own actions Able to do
Physical functions Able to do
Recognize functions Mostly able to do
Social adaptability Mostly able to do