Stem Cell Medical Reports

The Journal of Pediatrics · 2020-05-19

A Phase II Randomized Clinical Trial of Intravenous Umbilical Cord Blood Infusion for Children With Autism Spectrum Disorder:

Geraldine Dawson, Jessica M. Sun, Jennifer Baker, Kimberly Carpenter, Scott Compton, Megan Deaver, Lauren Franz, Nicole Heilbron, Brianna Herold, Joseph Horrigan, Jill Howard, Andrzej Kosinski, Samantha Major, Michael Murias, Kristin Page, Vinod K. Prasad, Maura Sabatos-DeVito, Fred Sanfilippo, Linmarie Sikich, Ryan Simmons, Allen Song, Saritha Vermeer, Barbara Waters-Pick, Jesse Troy, and Joanne Kurtzberg.

Stem Cells Translational Medicine · 2020-06-12

Infusion of Human Umbilical Cord Tissue Mesenchymal Stromal Cells in Children With Autism Spectrum Disorder:

Jessica M. Sun, Geraldine Dawson, Lauren Franz, Jill Howard, Colleen McLaughlin, Bethany Kistler, Barbara Waters-Pick, Norin Meadows, Jesse Troy, and Joanne Kurtzberg.

Stem Cell Research & Therapy · 2023-04-27

Immunomodulatory Amnion-Derived Mesenchymal Stromal Cells Preserve Muscle Function in a Mouse Model of Duchenne Muscular Dystrophy

Yuko Nitahara-Kasahara, Soya Nakayama, Koichi Kimura, Sho Yamaguchi, Yuko Kakiuchi, Chikako Nito, Masahiro Hayashi, Tomoyuki Nakaishi, Yasuyoshi Ueda, and Takashi Okada.

Stem Cells Translational Medicine · 2021-07-27

The Use of Umbilical Cord-Derived Mesenchymal Stem Cells in Patients With Muscular Dystrophies: Results From Compassionate Use in Real-Life Settings

Beata Świątkowska-Flis, Izabela Zdolińska-Malinowska, Dominika Sługocka, and Dariusz Boruczkowski.

Stem Cells Translational Medicine · 2024-02-16

A Phase I Dose-Escalation Clinical Trial to Assess the Safety and Efficacy of Umbilical Cord-Derived Mesenchymal Stromal Cells in Knee Osteoarthritis

Jose Matas, Cynthia García, Daniela Poblete, Rolando Vernal, Alexander Ortloff, Noymar Luque-Campos, Yessia Hidalgo, Jimena Cuenca, Catalina Infante, Maria Ignacia Cadiz, Maroun Khoury, Patricia Luz-Crawford and Francisco Espinoza.

Ophthalmic Genetics · 2023-10-09

Aberrant Gene Expression Yet Undiminished Retinal Ganglion Cell Genesis in iPSC-Derived Models of Optic Nerve Hypoplasia

Jennifer G. Aparicio, Hanno Hopp, Narine Harutyunyan, Carly Stewart, David Cobrinik, and Mark Borchert.

Stem Cell Research & Therapy · 2024-04-01

Administration of Adipose-Derived Stem Cells Extracellular Vesicles in a Murine Model of Spinal Muscular Atrophy: Effects of a New Potential Therapeutic Strategy

Federica Virla, Ermanna Turano, Ilaria Scambi, Lorenzo Schiaffino, Marina Boido, and Raffaella Mariotti.

Biomedicines · 2026-01-09

Advances in Fetal Repair of Spina Bifida Integrating Prenatal Surgery, Stem Cells, and Biomaterials

Aleksandra Evangelista, Luigi Ruccolo, Valeria Friuli, Marco Benazzo, Bice Conti, and Silvia Pisani.

Frontiers in Cellular Neuroscience · 2025-04-16

Assessment of Mesenchymal Stem Cells for the Treatment of Spinal Cord Injury: A Systematic Review and Network Meta-Analysis

Runfang Wang, Yiding Wang, Fangning Yan, Jinqing Sun and Tianyu Zhang.

Orphanet Journal of Rare Diseases · 2025-04-03

Biological Pathways Leading to Septo-Optic Dysplasia: A Review

Ludovica Pasca, Davide Politano, Federica Morelli, Jessica Garau, Sabrina Signorini, Enza Maria Valente, Renato Borgatti, and Romina Romaniello.

Neural Regeneration Research · 2025-06-19

Cell-Based Therapies for Traumatic Optic Neuropathy: Recent Advances, Challenges, and Perspectives

Yuanhui Wang, Moxin Chen, Zhimin Tang and Ping Gu.

Nature Medicine · 2023-11-02

Cell-Based Versus Corticosteroid Injections for Knee Pain in Osteoarthritis: A Randomized Phase 3 Trial

Ken Mautner, Michael Gottschalk, Scott D. Boden, Alison Akard, Won C. Bae, Lora Black, Blake Boggess, Paramita Chatterjee, Christine B. Chung, Kirk A. Easley, Greg Gibson, Josh Hackel, Katie Jensen, Linda Kippner, Chad Kurtenbach, Joanne Kurtzberg, R. Amadeus Mason, Benjamin Noonan, Krishnendu Roy, Verle Valentine, Carolyn Yeago and Hicham Drissi.

Cellular and Molecular Life Sciences · 2025-10-11

Cell Therapy for Duchenne Muscular Dystrophy: Promises, Challenges, and Controversies

Agnieszka Łoboda and Józef Dulak.

Cells · 2025-05-12

Clinical Evidence of Mesenchymal Stromal Cells for Cerebral Palsy: Scoping Review With Meta-Analysis of Efficacy in Gross Motor Outcomes

Madison C. B. Paton, Alexandra R. Griffin, Remy Blatch-Williams, Annabel Webb, Frances Verter, Pedro S. Couto, Alexey Bersenev, Russell C. Dale, Himanshu Popat, Iona Novak, and Megan Finch-Edmondson.

Pediatrics · 2025-04-11

Cord Blood Treatment for Children With Cerebral Palsy: Individual Participant Data Meta-Analysis

Megan Finch-Edmondson, Madison C. B. Paton, Annabel Webb, Mahmoud Reza Ashrafi, Remy K. Blatch-Williams, Charles S. Cox Jr, Kylie Crompton, Alexandra R. Griffin, MinYoung Kim, Steven Kosmach, Joanne Kurtzberg, Masoumeh Nouri, Mi Ri Suh, Jessica Sun, Morteza Zarrabi, and Iona Novak.

The Lancet · 2026-07-29

Deramiocel Heart-Derived Cellular Therapy in Advanced Duchenne Muscular Dystrophy (HOPE-3): A Phase 3, Randomised, Double-Blind, Placebo-Controlled Trial

Craig M McDonald, Chet Villa, Jonathan H Soslow, Kati Maharry, Nathaniel Hogan, Michael Binks, Kevin C Berth, Kristi A Elliott, Michael Taylor, Kan N Hor, James Signorovich, Erik K Henricson, Han C Phan, Susan Apkon, Partha S Ghosh, Cuixia Tian, Aravindhan Veerapandiyan, Leigh Ramos-Platt, Katheryn Gambetta, Saunder M Bernes, Arun S Varadhachary, Susan T Iannaccone, Chamindra G Laverty, Seth J Perlman, Nancy E Bass, Kathryn Mosher, Russell J Butterfield, Katherine D Mathews, Rebecca J Scharf, Edward C Smith, Jane Anne Emerson, Eugenio Mercuri, Mark S Awadalla, Linda Marbán, and Eduardo Marbán, on behalf of the HOPE-3 Investigators.

Stem Cell Research & Therapy · 2026-06-19

Efficacy and Safety of Allogeneic Umbilical Cord Blood Mononuclear Cells in Children With Autism and Immune Dysregulation:

Ziyan Zhang, Guanglei Wang, Fang Han, Honghui Zhou, Yan Liang, Li Zhang, Ping Pang, Xinyu Cao, Peili Hu, Xinyun Yao, Chunhua Sun, Jing Wang, Xiuyu Shi, Linyan Hu, and Guang Yang.

Stem Cell Research & Therapy · 2025-03-07

Efficacy and Safety of Mesenchymal Stem Cells in Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Mumin Cao, Zhengkuan Ou, Renwang Sheng, Qianqian Wang, Xiangxu Chen, Cheng Zhang, Guangchun Dai, Hao Wang, Jiamin Li, Xihan Zhang, Yucheng Gao, Liu Shi and Yunfeng Rui.

Global Spine Journal · 2025-05-23

Efficacy of Mesenchymal and Embryonic Stem Cell Therapy for the Treatment of Spinal Cord Injury: A Systematic Review and Meta-Analysis of Human Studies

Zachary Troiani, Danielle E. Chipman, Thomas J. Ryan, Mohammad N. Haider, David Kowalski, Bilal Hasanspahic, Maxwell M. Scott, Emily K. Vallee and Christopher Lucasti.

EClinicalMedicine · 2020-01-09

Endocrine Morbidity in Midline Brain Defects: Differences Between Septo-Optic Dysplasia and Related Disorders

M. Cerbone, M. Güemes, A. Wade, N. Improda, and M. Dattani.

BMC Ophthalmology · 2024-07-29

Evaluating the Impact of Mesenchymal Stem Cell Therapy on Visual Acuity and Retinal Nerve Fiber Layer Thickness in Optic Neuropathy Patients: A Comprehensive Systematic Review and Meta-Analysis

Samira Chaibakhsh, Fatemeh Azimi, Alireza Shoae-Hassani, Parvin Niknam, Ali Ghamari, Samaneh Dehghan and Naveed Nilforushan.

Stem Cell Research & Therapy · 2025-08-29

Evaluation of Stem/Stromal Cell Transplantation Safety and Efficacy in Children Diagnosed With Cerebral Palsy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Ronak Fatahi, Fatemeh Heydarpour, Sepehr Moradi Motlagh, and Kamran Mansouri.

The Lancet · 2026-02-28

Feasibility and Safety of Cellular Therapy for In-Utero Repair of Myelomeningocele (CuRe Trial): A First-in-Human, Phase 1, Single-Arm Study

Diana L Farmer, Priyadarsini Kumar, Elizabeth Reynolds, Su Yeon Lee, Amy B Powne, Christopher D Pivetti, Marike Zwienenberg, Amelia S McLennan, Jan A Nolta, Erin G Brown, Payam Saadai, Shinjiro Hirose, and Aijun Wang.

Journal of Extracellular Vesicles · 2025-06-19

First-In-Human Application of Human Umbilical Cord-Derived Extracellular Vesicles in Tethered Spinal Cord Release Surgery

Matthias Krause, Janina Gburek-Augustat, Daniel Gräfe, Roman Metzger, Marco Ginzel, Christoph J. Griessenauer, Lukas Grassner, Daniel Weghuber, Johann Gradl, Daniela Auer, Tanja Schally, Stefan Rund, Carina Kals, Christina Folie, Elisabeth Bayer, Mario Gimona, and Eva Rohde.

Brain and Behavior · 2026-03-31

Human Umbilical Cord Blood Mesenchymal Stem Cells Ameliorate Autism-Like Behaviors in a Valproic Acid-Induced Mouse Model via the IGF-1/Akt Signaling Pathway:

Jie Tian, Hujing Deng, Zhoujing Hu, Guangzhen He, Juan Zhang, Feiyang Jiang, Jinyun Xu, Yong Wu, Hao Jiang, Ruibo Zhang, Lan Ren, and Jiaowei Gu.

Scientific Reports · 2026-05-19

Impact of Stem Cell Therapy on Brain Metabolic Profile in Cerebral Palsy Assessed by Magnetic Resonance Spectroscopy in a Randomized Clinical Trial

Melika Jameie, Neda Pak, Mehrdad Mozafar, Hadis Farazmand, Elaheh Khodadoust, Anahita Majmaa, Mobina Amanollahi, Morteza Zarrabi, Masoumeh Nouri, Masood Ghahvechi Akbari, Ali Reza Moaiedi, Reza Shervin Badv, Massoud Vosough, Amir Ali Hamidieh, Hadi Montazerlotfelahi, Ali Reza Tavasoli, Morteza Heidari, Safdar Masoomi, Fatemeh Zamani, and Mahmoud Reza Ashrafi.

BMC Musculoskeletal Disorders · 2025-12-29

Intra-Articular Injection of Umbilical Cord-Derived Mesenchymal Stem Cells Is Safe and Effective for Moderate to Severe Knee Osteoarthritis With Synovitis: A Double-Blinded and Randomized Controlled Trial

Wei Tong, Yangyang Shi, Dongcheng Wu, Jie Jia, E Xiang, Dongdong Xu, Wei Rao, Qin Hu, Qiwen Liao, Cuihong Xiao, Shuo Zheng, Weihua Xu and Hongtao Tian.

Nature Communications · 2024-04-01

Intrathecal Delivery of Adipose-Derived Mesenchymal Stem Cells in Traumatic Spinal Cord Injury: Phase I Trial

Mohamad Bydon, Wenchun Qu, F. M. Moinuddin, Christine L. Hunt, Kristin L. Garlanger, Ronald K. Reeves, Anthony J. Windebank, Kristin D. Zhao, Ryan Jarrah, Brandon C. Trammell, Sally El Sammak, Giorgos D. Michalopoulos, Konstantinos Katsos, Stephen P. Graepel, Kimberly L. Seidel-Miller, Lisa A. Beck, Ruple S. Laughlin and Allan B. Dietz.

eClinicalMedicine · 2026-04-13

Safety and Efficacy of Intravenous Onasemnogene Abeparvovec Gene Therapy in Patients With Spinal Muscular Atrophy Type 1: Interim Analysis From LT-001

Megan A. Waldrop, Roberto Bernardo Escudero, Lina Yang, Rebekah A. Camarata, Emily C. Branic, Lesa Mehl, Andreja Ilić, and Anne M. Connolly.

Stem Cell Research & Therapy · 2023-09-21

Intravitreal Allogeneic Mesenchymal Stem Cells: A Non-Randomized Phase II Clinical Trial for Acute Non-Arteritic Optic Neuropathy

Jose C. Pastor, Salvador Pastor-Idoate, Marina López-Paniagua, Marta Para, Francisco Blazquez, Esther Murgui, Verónica García and Rosa M. Coco-Martín.

The Lancet Regional Health - Europe · 2024-02-06

Long-Term Efficacy and Safety of Nusinersen in Adults With 5q Spinal Muscular Atrophy: A Prospective European Multinational Observational Study

René Günther, Claudia Diana Wurster, Svenja Brakemeier, Alma Osmanovic, Olivia Schreiber-Katz, Susanne Petri, Zeljko Uzelac, Miriam Hiebeler, Simone Thiele, Maggie C. Walter, Markus Weiler, Tobias Kessler, Maren Freigang, Hanna Sophie Lapp, Isabell Cordts, Paul Lingor, Marcus Deschauer, Andreas Hahn, Kyriakos Martakis, Robert Steinbach, Benjamin Ilse, Annekathrin Rödiger, Julia Bellut, Julia Nentwich, Daniel Zeller, Mohamad Tareq Muhandes, Tobias Baum, Jan Christoph Koch, Bertold Schrank, Sophie Fischer, Andreas Hermann, Christoph Kamm, Steffen Naegel, Alexander Mensch, Markus Weber, Christoph Neuwirth, Helmar C. Lehmann, Gilbert Wunderlich, Christian Stadler, Maike Tomforde, Annette George, Martin Groß, Astrid Pechmann, Janbernd Kirschner, Matthias Türk, Mareike Schimmel, Günther Bernert, Pascal Martin, Christian Rauscher, Gerd Meyer zu Hörste, Petra Baum, Wolfgang Löscher, Marina Flotats-Bastardas, Cornelia Köhler, Kristina Probst-Schendzielorz, Susanne Goldbach, Ulrike Schara-Schmidt, Wolfgang Müller-Felber, Hanns Lochmüller, Otgonzul von Velsen, Christoph Kleinschnitz, Albert C. Ludolph, and Tim Hagenacker.

Stem Cell Reviews and Reports · 2025-12-18

Long-Term Safety and Efficacy of Systemic DT-DEC01 Cell Therapy in Non-Ambulatory Duchenne Muscular Dystrophy Patients: A 24-Month Clinical Evaluation

Maria Siemionow, Grzegorz Biegański, Adam Niezgoda, Agnieszka Sobkowiak-Sobierajska, Jarosław Czarnota, Krzysztof Siemionow, Anna Ziemiecka, Katarzyna Bożyk, and Jacek Wachowiak.

Stem Cells Translational Medicine · 2026-08-05

Long-Term Safety of Intravenous Human Umbilical Cord Blood-Derived Mesenchymal Stem Cell Therapy in Rheumatoid Arthritis: A 5-Year Follow-Up Study

Eun Hye Park, Min Jung Kim, Kyung-Sun Kang and Kichul Shin.

Stem Cell Research & Therapy · 2023-12-12

Maintenance of the Synergistic Effects of Cord Blood Cells and Erythropoietin Combination Therapy After Additional Cord Blood Infusion in Children With Cerebral Palsy: 1-Year Open-Label Extension Study of Randomized Placebo-Controlled Trial

Mi Ri Suh, Kyunghoon Min, Kye Hee Cho, Jongwook Kim, Ikhyun Lim, Mijin Park, Eun-Min Noh, and Min Young Kim.

Journal of Translational Medicine · 2026-03-20

Mesenchymal Stem/Stromal Cell-Based Therapies for Autism Spectrum Disorder: Emerging Evidence and Clinical Prospects

Minghui Xu, Xiaohan Zhang, Yuqian Liu, Yue Yang, Zijing Zhou, Jun Ma, and Sanbing Shen.

CNS Neuroscience & Therapeutics · 2026-07-23

Mesenchymal Stem Cell-Based Therapy for Cerebellar Ataxia: From Bench to Bedside

Kyoungho Suk, Ho-Won Lee, and Sang Ryong Kim.

Biomedicines · 2026-03-26

Mesenchymal Stromal/Stem Cells in Chronic Incomplete Traumatic Spinal Cord Injury: A Phase I/II Double-Blind Placebo-Controlled Multicentre Trial

Fernando Martins Braga, Hatice Kumru, Jesús Benito-Penalva, Joaquim Vives, Ruth Coll Bonet, Wanbao Ge, Luciano Rodríguez, Margarita Codinach, Aurora de la Iglesia-López, Antonio Gómez-Rodríguez, José Javier Cid-Fernández, Antonio Montoto-Marqués and Joan Vidal Samsó.

World Journal of Stem Cells · 2025-05-26

Multiroute Administration of Wharton's Jelly Mesenchymal Stem Cells in Chronic Complete Spinal Cord Injury: A Phase I Safety and Feasibility Study

Necati Kaplan, Serdar Kabatas, Erdinç Civelek, Eyüp Can Savrunlu, Tolga Akkoc, Osman Boyalı, Erek Öztürk, Halil Can, Ali Genc and Erdal Karaöz.

Molecular Autism · 2023-07-25

Neurodevelopmental Impairments in Children With Septo-Optic Dysplasia Spectrum Conditions: A Systematic Review

Amy Mann, Arameh Aghababaie, Jennifer Kalitsi, Daniel Martins, Yannis Paloyelis, and Ritika R. Kapoor.

Stem Cell Research & Therapy · 2023-04-28

Outcomes of Autologous Bone Marrow Mononuclear Cell Administration in the Treatment of Neurologic Sequelae in Children With Spina Bifida

Liem Thanh Nguyen, Huong Thu Le, Kien Trung Nguyen, Hang Thi Bui, Anh Phuong Thi Nguyen, Doan Van Ngo, Duc Minh Hoang, and Minh Duy Ngo.

Clinical Endocrinology · 2024-08-04

Pituitary Deficiencies Related to Optic Nerve Hypoplasia and Visual Acuity

Alison Murray, Terry Schwartz, Lindsey Hornung, and Sarah Lawson.

Stem Cell Research & Therapy · 2024-11-09

Post-Symptomatic Administration of hMSCs Exerts Therapeutic Effects in SCA2 Mice

Sehwan Kim, Chanchal Sharma, Jungwan Hong, Jong-Heon Kim, Youngpyo Nam, Min Sung Kim, Tae Yong Lee, Kyung-Suk Kim, Kyoungho Suk, Ho-Won Lee and Sang Ryong Kim.

The Lancet · 2022-03-12

Repeated Intravenous Cardiosphere-Derived Cell Therapy in Late-Stage Duchenne Muscular Dystrophy (HOPE-2): A Multicentre, Randomised, Double-Blind, Placebo-Controlled, Phase 2 Trial

Craig M McDonald, Eduardo Marbán, Suzanne Hendrix, Nathaniel Hogan, Rachel Ruckdeschel Smith, Michelle Eagle, Richard S Finkel, Cuixia Tian, Joanne Janas, Matthew M Harmelink, Arun S Varadhachary, Michael D Taylor, Kan N Hor, Oscar H Mayer, Erik K Henricson, Pat Furlong, Deborah D Ascheim, Siegfried Rogy, Paula Williams, Linda Marbán, and the HOPE-2 Study Group.

Molecular Neurodegeneration · 2023-09-21

Retinal Ganglion Cell Repopulation for Vision Restoration in Optic Neuropathy: A Roadmap From the RReSTORe Consortium

Jonathan R. Soucy, Erika A. Aguzzi, Julie Cho, Michael James Gilhooley, Casey Keuthan, Ziming Luo, Aboozar Monavarfeshani, Meher A. Saleem, Xue-Wei Wang, Juilette Wohlschlegel, The RReSTORe Consortium, Petr Baranov, Adriana Di Polo, Brad Fortune, Kimberly K. Gokoffski, Jeffrey L. Goldberg, William Guido, Alex L. Kolodkin, Carol A. Mason, Yvonne Ou, Thomas A. Reh, Ahmara G. Ross, Brian C. Samuels, Derek Welsbie, Donald J. Zack and Thomas V. Johnson.

Stem Cell Research & Therapy · 2024-11-20

Safety and Efficacy of Human Umbilical Cord-Derived Mesenchymal Stromal Cells in Fetal Ovine Myelomeningocele Repair

Yoann Athiel, Laura Cariot, Jean-Marie Jouannic, Corentin Maillet, Vincent Mauffré, Clovis Adam, Hélène Huet, Jérôme Larghero, Justine Nasone, and Lucie Guilbaud.

Biologics: Targets and Therapy · 2026-03-31

Safety and Efficacy of Mesenchymal Stem Cell Therapy in Multiple System Atrophy: Systematic Review

Noon Elimam, Shams Samih Albarari, Yara Shaalan, Shazaa Mahmoud Elsheikh, Ainaa A Alzamari, Nourhan Elmekkawi, Rahaf Mogahed, and Razan H Alghuweiri.

Stem Cell Research & Therapy · 2026-07-10

Safety and Preliminary Efficacy of Autologous Bone Marrow-Derived Mesenchymal Stem Cell Transplantation in Hereditary Cerebellar Ataxia: Phase I/IIa Clinical Trial

Abbas Shapouri Moghaddam, Jalil Tavakol-Afshari, Najmeh Kaffash Farkhad, Majid Mojarrad, Maryam Eslami, Shahram Savad, Mohammad Ali Khodadoust, Ala Orafaie, Mohammadreza Sobhani, Akram Farmanbar, Mohammad Dashtkoohi, Hamid Khodayari, Delaram Hassani, Shahrzad Najafi, Parizad Najafi, Jürgen Hescheler, Karim Nayernia and Amirreza Boroumand.

Journal of Clinical Neurology · 2025-01-01

Safety and Tolerability of Wharton's Jelly-Derived Mesenchymal Stem Cells for Patients With Duchenne Muscular Dystrophy: A Phase 1 Clinical Study

Jiwon Lee, Sang Eon Park, Mira Kim, Hyeongseop Kim, Jeong-Yi Kwon, Hong Bae Jeon, Jong Wook Chang, and Jeehun Lee.

Frontiers in Molecular Medicine · 2026-08-25

Spinal Muscular Atrophy in the Disease-Modifying Therapy Era: Successes, Limitations and Future Directions

Madison M. Sexton, Emma W. Crow, and Congyue Annie Peng.

European Psychiatry (European Psychiatric Association congress abstract, Vol. 69 Suppl. 1, p. S534) · 2026-07-31

Stem Cell Therapy for Autism Spectrum Disorder: A Systematic Review and Meta-Analysis of Clinical Evidence (Conference Abstract)

S. M. M. Fekrat, V. Sharma, S. Prasad, and S. Gunturu.

Annals of Clinical and Translational Neurology · 2026-07-13

Stem Cell Transplantation in Friedreich Ataxia: Cure for Leukemia but No Effect on Neurological Progression

Alexandra Gitman, Niyati Bhandari, Maria Castellaro, Kim Schadt, María Cancio, and David R. Lynch.

Frontiers in Cell and Developmental Biology · 2026-03-04

The Therapeutic Potential of Bone Marrow Mesenchymal Stem Cells-Derived Exosomes for Retinal and Optic Nerve Diseases

Mingzhe Shi, Shounan Qi, Feifan Qi and Chenguang Wang.

Neuroprotection · 2025-12-22

Therapeutic Potential of Stem Cells in Pediatric Neurology: Insights From Clinical Trials

Daniel Bou Najm and Saada Alame.

Stem Cell Research & Therapy · 2026-07-30

Three Repeated Intrathecal Injections of Allogenic Umbilical Cord-Derived Mesenchymal Stromal Cells in Autism Spectrum Disorder: A Phase I Clinical Trial

Elaheh Khodadoust, Hadi Zarafshan, Masoumeh Nouri, Anahita Majmaa, Ali Khaleghi, Fatemeh Zamani, Milad Seyfi, Mohammad Amin Shahrbaf, Solaleh Samimi, Bahareh Sadri, Seyedeh Malihe Mahmoodi, Norouz Abdi, Ali Ghasemi, Mahmoud Reza Ashrafi, Morteza Zarrabi, Massoud Vosough, and Mohammad Reza Mohammadi.

Chulalongkorn University (Thailand), George Washington University (USA), Tohoku University (Japan) · 2025-01-01

Sex-Specific Effects of Prenatal BPA Exposure on Neural Stem Cells and Autism Risk

Kasidit Kasitipradit, Surangrat Thongkorn, Songphon Kanlayaprasit, Thanit Saeliw, Pattanachat Lertpeerapan, Pawinee Panjabud, Depicha Jindatip, Valerie W. Hu, Takako Kikkawa, Noriko Osumi, Tewarit Sarachana

Nature Medicine · 2025-03-10

Allogeneic Mesenchymal Stem Cell Therapy with Laromestrocel in Alzheimer's Disease: A Phase 2a Trial

Brian G. Rash, Kevin N. Ramdas, Anthony A. Oliva Jr.

Cell Stem Cell · 2025-03-06

Pre-clinical Safety and Efficacy of Human Induced Pluripotent Stem Cell-Derived Midbrain Dopaminergic Progenitor Cells for Parkinson's Disease

Jeha Jeon, Young Cha, Yean Ju Hong, In-Hee Lee, Heejin Jang, Sanghyeok Ko, Serhiy Naumenko, Minseon Kim, Hannah L. Ryu, Zenith Shrestha, Nayeon Lee, Tae-Yoon Park, HoeWon Park, Seo-Hyun Kim

Regenerative Medicine Journal (Taylor & Francis Group) · 2025-01-19

Industry Updates from the Field of Stem Cell Research and Regenerative Medicine November 2024 (Summary)

Dusko Ilic and Mirjana Liovic

New England Journal of Medicine · 2024-12-09

Lentiviral Gene Therapy with CD34+ Hematopoietic Cells for Hemophilia A

Alok Srivastava, M.D., Aby Abraham, D.M., Fouzia Aboobacker, D.M., Gurbind Singh, Ph.D., Tulasi Geevar, M.D., Uday Kulkarni, D.M., Sushil Selvarajan, D.M. , Trent Spencer, Ph.D.

Fondation du Rein, ANR eCellFrance · 2024-12-17

Allogeneic Umbilical Cord-Derived Mesenchymal Stromal Cells in Severe Systemic Lupus Erythematosus: A Phase 1 Trial

Prof Dominique Farge, MD, Lucie Biard, PhDd, Ben Weil, EngDe, Virginie Girault, PhD, Pauline Lansiaux, PhD, Ingrid Munia, MS, Séverine Loisel, PhD, Catney Charles, BSca, Judikael Saout, PhD

The Lancet · 2024-11-16

Induced Pluripotent Stem-Cell-Derived Corneal Epithelium for Transplant Surgery

Takeshi Soma, MDa, Yoshinori Oie, MDa, Hiroshi Takayanagi, MSa, Shoko Matsubara, BA, Tomomi Yamada, PhDd, Masaki Nomura, PhD

Nature Biotechnology · 2024-09-02

Creating Functional Hematopoietic Stem Cells from iPS Cells for Blood Disorders and Beyond

Elizabeth S. Ng, Gulcan Sarila, Jacky Y. Li, Hasindu S. Edirisinghe, Ritika Saxena, Shicheng Sun, Freya F. Bruveris, Tanya Labonne, Nerida Sleebs, Alexander Maytum, Raymond Y. Yow, Chantelle Inguanti, Ali Motazedian, Vincenzo Calvanese, Sandra Capellera-G

Aspen Neuroscience, Inc. · 2024-07-26

Preclinical Evaluation of Transaxial Intramutaminal Trajectory for Enhanced Distribution of Grafted Cells in Parkinson’s Disease Summary

Marina E. Emborg, MD, PhD, and colleagues

Research was conducted in partnership with the Australian Regenerative Medicine Institute. · 2024-01-20

Summary of the Report "MSCs Mediate Long-term Efficacy in a Crohn’s Disease Model by Sustained Anti-inflammatory Macrophage Programming via Efferocytosis

Maneesh Dave, Atul Dev, Rodrigo A. Somoza, et al.

Xianjing Chu, Wentao Tian, Jiaoyang Ning, Gang Xiao, Yunqi Zhou, Ziqi Wang, Zhuofan Zhai, Guilong Tanzhu, Jie Yang & Rongrong Zhou · 2024-07-05

Stem Cell Treatments Leading the Charge to Cure Cancer

2024-04-30

Stem Cells Used to Succesfully treat Type 2 Diabetes

Jiaying Wu, Tuo Li, Meng Guo, Junsong Ji, Xiaoxi Meng, Tianlong Fu, Tengfei Nie, Tongkun Wei, Ying Zhou, Weihua Dong, Ming Zhang, Yongquan Shi, Xin Cheng, Hao Yin & Clinical Group

This report is an invited article and was externally peer-reviewed, with no specific commissioning body mentioned. · 2021-12-16

Stem cell therapy: A promising treatment for COVID-19 (Summary)

Zhi-Xue Zheng

The Fund project of University of South China for Prevention and Control of COVID‐19 The Scientific Research Fund Project of Hunan Provincial Health Commission The Special Fundamental Research Project of COVID‐19 Prevention and Control of Hengyang Science · 2023-08-09

Safety and efficacy of mesenchymal stem cells in COVID‐19 patients: A systematic review and meta‐analysis (Summary)

Cai Yan, Minjie Hu, Rongjuan Dai

The National Key Research and Development Program of China, The Innovation Platform for Academicians of Hainan Province, and the Fund of National Clinical Center for Infectious Diseases, PLA General Hospital. · 2023-05-10

Human mesenchymal stem cell therapy in severe COVID-19 patients Report

Tian-Tian Li, Bo Zhang, Hui Fang, Ming Shi, Wei-Qi Yao, Yuanyuan Li, Chao Zhang, Jinwen Song, Lei Huang, Zhe Xu, Xin Yuan, Jun-Liang Fu, Cheng Zhen, Yu Zhang, Ze-Rui Wang, Zi-Ying Zhang, Meng-Qi Yuan, Tengyun Dong, Ruidan Bai, Lulu Zhao, Jianming Cai, Jin

2020-10-12

Stem cell therapy for muscular dystrophies

Stefano Biressi, Antonio Filareto, Thomas A. Rando

2013-09-10

A clinical study shows safety and efficacy of autologous bone marrow mononuclear cell therapy to improve quality of life in muscular dystrophy patients

Alok Sharma, Hemangi Sane, Prerna Badhe, Nandini Gokulchandran, Pooja Kulkarni, Mamta Lohiya, Hema Biju, V C Jacob

2018-10-26

Efficacy of stem cell therapy in ambulatory and nonambulatory children with Duchenne muscular dystrophy

Alper Dai, Osman Baspinar, Ahmet Yeşilyurt, Eda Sun, Çiğdem İnci Aydemir, Olga Nehir Öztel, Davut Unsal Capkan, Ferda Pinarli, Abdullah Agar, Erdal Karaöz

2014-03-28

Autologous bone marrow mononuclear cell transplantation in Duchenne muscular dystrophy

Alok Sharma, Hemangi Sane, Amruta Paranjape, Khushboo Bhagawanani, Nandini Gokulchandran, Prerna Badhe

2015-07-08

Duchenne Muscular Dystrophy — Sienkiewicz et al.

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Mayo Clinic · 2021-09-01

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Mayo clinic · 2021-09-01

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Improvement by Human Oligodendrocyte Progenitor Cells of Neurobehavioral Disorders in an Experimental Model of Neonatal Periventricular Leukomalacia

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Stem Cell Treatment and Cerebral Palsy

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Mayo Clinic · 2022-08-09

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