Last Updated on: 4th September 2024, 05:12 pm
Summary
| Diagnosis | Sex | Age | Nationality |
|---|---|---|---|
| Cerebral Palsy | Male | 9 years | Polish |
| Injections | Cell type | Admission date | Discharge date |
| 7 | UCBSC | February 10th 2019 | March 3rd 2019 |
Medical history
This new-born male baby was born by caesarean section from a complicated pregnancy at 32 weeks of gestation due to fetal bradycardia (low fetal heart rate). At birth, the new-born had symptoms of intermediate degree asphyxia and was later on diagnosed with hemorrhagic hydrocephalus which he was treated for, as well as hypoxic ischemic encephalopathy.
Condition On Admission
The patient could understand commands but was only able to speak single words. He could only move with a lot of assistance and could not walk. He could however sit independently. He had severe spasticity and coordination issues. Concentration was poor.
Treatment Schedule
The patient received 6 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) and intrathecal injections, as per the schedule below. In addition to stem cell injections, the patient received a daily rehabilitation therapy program that included physiotherapy, aquatic therapy, transcranial magnetic stimulation, acupuncture and hyperbaric oxygen therapy.
| Number | Date | Cell Type | Delivery Method | Side Effects |
|---|---|---|---|---|
| 1 | 2019-02-11 | UCBSC | Intravenous Injection | none reported |
| 2 | 2019-02-13 | UCBSC | Intravenous Injection | none reported |
| 3 | 2019-02-15 | UCBSC | Intrathecal Injection | none reported |
| 4 | 2019-02-18 | UCBSC | Intrathecal Injection | none reported |
| 5 | 2019-02-22 | UCBSC | Intrathecal Injection | none reported |
| 6 | 2019-02-25 | UCBSC | Intrathecal Injection | none reported |
| 7 | 2019-03-01 | UCBSC | Intravenous Injection | none reported |
Condition at discharge
The patient has stronger trunk muscles which allow him to better control his whole body when sitting on a therapeutic ball as he can now strongly move his body in different directions with minimal support. The patient has shown improvement in standing balance as well as he can stand longer and in a more stable way. His concentration has improved as he can now focus on an activity from 3 to 5 minutes compared to an attention span of 1 minute initially. Moreover, regarding his hand function, he can now voluntarily open his left hand to grasp and release an object more often.
Condition 6 months after treatment
The patient’s parents mentioned: “He walks better on our balcony, he is using his left hand more often, he can pull himself up. He is more focused and calm as well. He can now combine two words which he couldn’t do before. His doctor observed a significant improvement in his condition.
Condition 12 months after treatment
At the 12 month follow up point the patient’s parents reported: “He moves better, when we hold his hands, he walks better, he can maintain a correct posture”. In addition, please see an excerpt from the patient’s 12 month assessment below (filled by his parents):
| Symptom | Assessment of Improvement |
| Appetite | Significant improvement |
| Balance | Moderate improvement |
| Bladder control | Significant improvement |
| Crawling | Significant improvement |
| Drooling | Small improvement |
| Head control | Significant improvement |
| Involuntary movements | Moderate improvement |
| Learning disability | Moderate improvement |
| Limb muscle strength | Significant improvement |
| Mood disorder | Moderate improvement |
| Range of movement | Significant improvement |
| Spasticity | Moderate improvement |
| Speech (babbling for infants) | Significant improvement |
| Standing up | Significant improvement |
| Swallowing | Significant improvement |
| Trunk muscle strength | Moderate improvement |
| Walking | Significant improvement |