Summary
Diagnosis
Sex
Age
Nationality
Optic Nerve Hypoplasia (ONH) / Septooptic Dysplasia (SOD)
Female
6 years
USA
Injections
Cell type
Admission date
Discharge date
7
2018-12-20
2019-01-04
Condition On Admission
Baylie had learning disability. She had Diabetes Insipidus and autistic behaviors. She did not talk but could understand. She was affected by constipation and lack of sleep. She did not walk and she was totally blind from birth but she gained a little bit of sight overtime.
Treatment Schedule
Patient received 6 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) injection and lumbar puncture (LP), as per the schedule below:
Number
Date
Cell Type
Delivery Method
Side Effects
1
2018-12-21
none reported
2
2018-12-25
none reported
3
2018-12-25
none reported
4
2018-12-28
none reported
5
2018-12-28
none reported
6
2020-01-02
none reported
7
None
Condition 6 months after treatment
Condition 6 months after treatment: At the 6 month follow up point, Baylie’s family mentioned: “Baylie can now see up to about 2 to 3 feet. She is starting to focus on things and look at them instead of feeling for them. Amazing improvement. Baylie has muscle tone improvement. She is definitely more active and her posture is way better.” Please see an excerpt from the family’s 6 month assessment below:
Symptom
Parents’ Assessment of Improvement
Ability to focus eyes quickly
Moderate improvement
Ability to keep eyes focused for a long time
Small improvement
Ability to see hand movement
Significant improvement
Ability to see things at a close distance
Significant improvement
Ability to see things at a far distance
Moderate improvements
Ability to see things clearly
Moderate improvements
Able to count fingers
Significant improvement
Blindness
Significant improvement
Colour vision
Significant improvement
Light perception
Significant improvement
Night vision
Moderate improvements
Nystagmus
Moderate improvements
Strabismus
Small improvement
Vision in left eye
Significant improvement
Vision in right eye
Significant improvement
Visual field
Significant improvement
