Ataxia
Autism
Cancer
Cerebral Palsy
Covid 19
Crohn’s Disease
Diabetes
Duchenne muscular dystrophy (DMD)
Muscular Dystrophy
Optic Nerve Atrophy
Parkinsons
Spina Bifida
Spinal Cord Injury
Spinal muscular atrophy
Spinal Muscular Atrophy (SMA)

Creating Functional Hematopoietic Stem Cells from iPS Cells for Blood Disorders and Beyond (Report summary)

Author or authors of report : Elizabeth S. Ng, Gulcan Sarila, Jacky Y. Li, Hasindu S. Edirisinghe, Ritika Saxena, Shicheng Sun, Freya F. Bruveris, Tanya Labonne, Nerida Sleebs, Alexander Maytum, Raymond Y. Yow, Chantelle Inguanti, Ali Motazedian, Vincenzo Calvanese, Sandra Capellera-G
Date of report : 2024-09-02
Diabetes, Spinal Cord Injury
Nature Biotechnology
Objectives of the Report The report aimed to develop a reliable method to turn human induced pluripotent stem cells (iPS cells) into functional hematopoietic stem cells (HSCs). These cells needed
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Preclinical Evaluation of Transaxial Intramutaminal Trajectory for Enhanced Distribution of Grafted Cells in Parkinson’s Disease Summary

Author or authors of report : Marina E. Emborg, MD, PhD, and colleagues
Date of report : 2024-07-26
Parkinsons
Aspen Neuroscience, Inc.
Introduction This comprehensive study, conducted by Marina E. Emborg and colleagues, published on July 26, 2024, investigates a novel surgical technique for administering human-induced pluripotent stem cell-derived dopaminergic neuroprogenitor cells
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Summary of the Report “MSCs Mediate Long-term Efficacy in a Crohn’s Disease Model by Sustained Anti-inflammatory Macrophage Programming via Efferocytosis

Author or authors of report : Maneesh Dave, Atul Dev, Rodrigo A. Somoza, et al.
Date of report : 2024-01-20
Crohn’s Disease
Research was conducted in partnership with the Australian Regenerative Medicine Institute.
Introduction and Background The study, led by Maneesh Dave and a diverse team of researchers, explores the therapeutic potential of human bone marrow-derived mesenchymal stem cells (hMSCs) in treating Crohn’s
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Stem Cell Treatments Leading the Charge to Cure Cancer

Date of report : 2024-07-05
Cancer
Xianjing Chu, Wentao Tian, Jiaoyang Ning, Gang Xiao, Yunqi Zhou, Ziqi Wang, Zhuofan Zhai, Guilong Tanzhu, Jie Yang & Rongrong Zhou
Cancer stem cells (CSCs), a small subset of cells within tumors, possess self-renewal capabilities and play a crucial role in tumorigenesis, metastasis, and therapeutic resistance. These cells contribute significantly to
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Stem Cells Used to Succesfully treat Type 2 Diabetes

Author or authors of report : Jiaying Wu, Tuo Li, Meng Guo, Junsong Ji, Xiaoxi Meng, Tianlong Fu, Tengfei Nie, Tongkun Wei, Ying Zhou, Weihua Dong, Ming Zhang, Yongquan Shi, Xin Cheng, Hao Yin & Clinical Group
Date of report : 2024-04-30
Diabetes
The report details a study that involved the treatment of a type 2 diabetic (T2D) patient using personalized endoderm stem cell-derived islet tissues (E-islets). The patient, a 59-year-old man with
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Stem cell therapy: A promising treatment for COVID-19 (Summary)

Author or authors of report : Zhi-Xue Zheng
Date of report : 2021-12-16
Covid 19
This report is an invited article and was externally peer-reviewed, with no specific commissioning body mentioned.
Summary of the Main Points/Findings: Background and Objective: The article reviews the potential of mesenchymal stem cell (MSC) therapy as a treatment for COVID-19. COVID-19, caused by SARS-CoV-2, has become
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Safety and efficacy of mesenchymal stem cells in COVID‐19 patients: A systematic review and meta‐analysis (Summary)

Author or authors of report : Cai Yan, Minjie Hu, Rongjuan Dai
Date of report : 2023-08-09
Covid 19
The Fund project of University of South China for Prevention and Control of COVID‐19 The Scientific Research Fund Project of Hunan Provincial Health Commission The Special Fundamental Research Project of COVID‐19 Prevention and Control of Hengyang Science
Summary of the Main Points/Findings: Background and Objective: The study titled "Safety and efficacy of mesenchymal stem cells in COVID‐19 patients: A systematic review and meta-analysis" aimed to evaluate the
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Human mesenchymal stem cell therapy in severe COVID-19 patients Report

Author or authors of report : Tian-Tian Li, Bo Zhang, Hui Fang, Ming Shi, Wei-Qi Yao, Yuanyuan Li, Chao Zhang, Jinwen Song, Lei Huang, Zhe Xu, Xin Yuan, Jun-Liang Fu, Cheng Zhen, Yu Zhang, Ze-Rui Wang, Zi-Ying Zhang, Meng-Qi Yuan, Tengyun Dong, Ruidan Bai, Lulu Zhao, Jianming Cai, Jin
Date of report : 2023-05-10
Covid 19
The National Key Research and Development Program of China, The Innovation Platform for Academicians of Hainan Province, and the Fund of National Clinical Center for Infectious Diseases, PLA General Hospital.
Summary of the Main Points/Findings: Background and Objective: The study aimed to evaluate the long-term safety and efficacy of human mesenchymal stem cell (MSC) treatment in severe COVID-19 patients over
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Stem cell therapy for muscular dystrophies Report Summary

Author or authors of report : Stefano Biressi, Antonio Filareto, Thomas A. Rando
Date of report : 2020-10-12
Muscular Dystrophy
Abstract: Muscular dystrophies are a diverse group of genetic diseases marked by progressive degeneration of skeletal and cardiac muscle. Despite extensive research into various therapeutic options, no definitive treatment has
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A clinical study shows safety and efficacy of autologous bone marrow mononuclear cell therapy to improve quality of life in muscular dystrophy patients Report Summary

Author or authors of report : Alok Sharma, Hemangi Sane, Prerna Badhe, Nandini Gokulchandran, Pooja Kulkarni, Mamta Lohiya, Hema Biju, V C Jacob
Date of report : 2013-09-10
Muscular Dystrophy
  Major Points: No Adverse Events: The study reported no significant adverse events, indicating the safety of the treatment. Neurological Improvements: Post-transplantation assessments showed improvements in trunk muscle strength, limb
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