What Factors May Affect the Success Stem Cell Therapy for Spinal Muscular Atrophy?

What Factors May Affect the Success Stem Cell Therapy for Spinal Muscular Atrophy?

We have summarized the different factors that might affect your response to stem cell therapy, and how we at Beike Technology address each factor to ensure that we provide you with the highest efficacy using the safest procedure possible.

  • Dose/Number of stem cells: The higher the dose of stem cells – within limits of course – the better the response. At Beike Technology, we administer an optimum dose of around 120-400 Million Cells (depending on the child’s weight and age) for SMA.

  • Route/Method of administration: Studies have shown that combining intrathecal injection (through lumbar puncture directly within the brain’s CSF) with the traditional intravenous route provides a better response than administering intravenous injections alone (which causes stem cells to go to other organs than the brain before reaching the brain). Therefore, at Beike Technology, we use both intravenous and intrathecal routes concomitantly in order to obtain maximal efficacy; while ensuring the least possible side effects or toxicity.

  • Type of Stem Cells used: Both umbilical cord-based stem cells, which we use at Beike Technology, and bone marrow stem cells have better-proven efficacy in SMA compared to other types of stem cells.

  •  Timing of stem cell transplantation: Early intervention is crucial for people with SMA. Therefore, we recommend early intervention soon after diagnosis depending on the type of SMA your child has.

  • Follow-up Time: Significant benefits from stem cell therapy in patients with SMA begin appearing around 4 weeks after stem cell therapy, and most people reach their full potential around 3 months after treatment. At Beike Technology, even after discharge, we provide you with a full follow-up program beginning as early as one month and up to one year after transplantation. You have complete access to our professional team even after you leave our center.

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